Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a genetic disease caused by red blood cell destruction and hemolysis. Patients often get sick due to eating broad beans, so it is also commonly known as "broad bean disease". Neonatal jaundice, broad bean disease, drug-induced hemolysis, infectious hemolysis, non-spherical cell hemolytic anemia and other clinical types. Severe acute hemolytic anemia induced by G6PD deficiency is caused by excessive red blood cell destruction. If not treated in time, it can cause liver, kidney, or heart failure, or even death.

  "Expert Consensus for Screening, Diagnosis and Treatment of Glucose-6-Phosphate Dehydrogenase Deficiency in Newborns" mentioned that G6PD deficiency is the same as normal people when there is no incentive to not develop disease, but if the disease also causes subsequent diseases It may cause serious consequences, so the key to prevention and treatment of the disease is prevention. The common G6PD enzyme activity test cannot be determined for female heterozygotes, and genetic diagnosis is a reliable method of diagnosis. G6PD deficiency has become one of the newborn screening projects, especially cases that have appeared in the family, and must be paid attention to. Newborns should be screened as soon as possible.